In this episode, Eunan McKinney discusses with Carina Ferreira-Borges, Programme Manager, Alcohol and Illicit Drugs & Prison Health, WHO European Office for Prevention and Control of Noncommunicable Diseases; Colin Angus, Senior Research Fellow, Sheffield Alcohol Research Group, University of Sheffield, and Prof. Karine Gallopel-Morvan, School of Public Health (Rennes, France); and Honorary Professor at the University of Stirling (Scotland), a number of issues relating to the development of progressive alcohol policy, the rational of the WHO’s policy “best buys’ for national implementation and the challenges that lie ahead for the next phase of global and regional strategies to reduce harmful use of alcohol.